Headshot of Caterina Brindicci, Senior Vice President and Global Head of Respiratory & Immunology Late-Stage Development, BioPharmaceuticals R&D at AstraZeneca

Our work at AstraZeneca is among the most exciting I’ve experienced in my 20+ years spent in research. We have a rich and growing pipeline of new molecular entities and marketed therapies that have the potential to address unmet needs, including in hard-to-treat diseases. Every day, we are pushing the boundaries of science and challenging the status quo to deliver practice-changing medicines.

As AstraZeneca and Alexion Chief Medical Officer, I am responsible for ensuring that patients, physicians and regulatory agencies are provided with information on the safe and appropriate use of our medicines. I lead patient safety and quality assurance activities for our entire portfolio – from investigational new drugs to established products.

Additionally, as Oncology Chief Development Officer, I lead AstraZeneca’s late-stage Oncology portfolio of innovative medicines and immunotherapies through global clinical development and regulatory submissions. In this role, I oversee a team of clinical development and operations colleagues around the world, who are currently responsible for a broad portfolio of potential medicines, and more than 160 studies spanning multiple Oncology indications.

Before joining AstraZeneca, I held a variety of clinical development leadership roles at Pfizer and at Novartis Pharmaceuticals. Over the last several years, I have lectured extensively on topics including immunotherapy clinical trials, breast cancer and clinical development of PI3K inhibitors. I have published on a wide range of cancer topics, authoring 50 peer-reviewed papers and more than 100 conference abstracts. I have also generated several patents for cancer treatment combinations and regimens.

A medical oncologist by training, I earned my medical degree from Marche Polytechnic University and received Medical Oncology training at the Royal Marsden Hospital, Kaplan Comprehensive Cancer Center and the European Institute of Oncology.

Ensuring patient safety has always been the number one priority at AstraZeneca and a leading focus of my work as an oncologist. Bringing safe, high quality, practice-changing treatments to patients is my passion and what drives me every day – together with the thought that we are transforming outcomes in cancer, and getting closer to finding a cure.

Cristian Massacesi Chief Medical Officer and Oncology Chief Development Officer, AstraZeneca

2008-2014:

Several Novartis awards including: President’s Award, Vision Award and Region Europe Award

1999:

Italian League Against Cancer’s Leonida Gennarelli Grant

1998:

A. Girombelli Prize for Best Oncology Dissertation




Headshot of Dr. Cristian Massacesi, Senior Vice President, Head of Late Stage Development Oncology at AstraZeneca

CURRENT ROLE

Chief Medical Officer and Oncology Chief Development Officer, AstraZeneca

2019 - 2021

Senior Vice President and Head of Late Development Oncology, AstraZeneca. Led, grew and steered the acceleration of AstraZeneca’s innovative late-stage Oncology portfolio through global clinical development and regulatory submissions

2017 - 2019

Led multiple development programs and submissions with small molecule and immunotherapy in lung cancer, head and neck cancer, haematological malignancies and innovative combinations as Vice President, Medicine Team Leader, Oncology for Pfizer

2010 - 2017

Held increasing levels of responsibility in Oncology Global Development at Novartis: Vice-President, Senior Global Clinical Program Head, leading clinical development of the PI3Ki portfolio, including multiple submissions and registrational studies and headed the Immunotherapy Center of Excellence; Paris Oncology Site head for a global full-development group across functions and portfolio

 Featured publications

Veeva ID: Z4-56919
Date of preparation: August 2023